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Norgesic® Forte, a known and trusted name. Orphenadrine Citrate, Aspirin and Caffeine, a non-controlled combination formulation for mild to moderate acute muscle aches and pain, that has been prescribed over 3 million times.

Patients will receive the FDA approved Reference Standard generic tablets when using the dispensing pharmacy network. A hassle free experience for Prescribers and Patients.

Norgesic® Forte is indicated as an adjunct to rest, physical therapy, and other measures to relieve acute musculoskeletal pain. Norgesic® Forte does not directly relax muscles. The mechanism of action of orphenadrine is not clearly identified, but may be related to its analgesic properties.

Living With Pain

Defining Musculoskeletal Pain

Musculoskeletal pain is pain that affects the muscles, ligaments, tendons, and bones.

Examples of Musculoskeletal Pain

Villa-Forte, A. Musculoskeletal Pain. Merck Manual Consumer Version. Updated 2/2021. Accessed 5/2021.


What is the most important information I should know about Norgesic® Forte?

Norgesic® Forte tablets may cause serious side effects, including:

  • Rare but serious bleeding due to the aspirin content
  • Life-threatening skin reactions
  • Life-threatening allergic reactions

Stop taking Norgesic® Forte and call your healthcare provider or get emergency help right away if you have any of these symptoms: rash, fever, trouble breathing, or swelling of the face, lips, tongue, or throat.

Use caution until you know how Norgesic® Forte affects you. It may impair your ability to drive or use other machinery.

Do not take Norgesic® Forte if you have any of the following:

  • Glaucoma (an eye disease)
  • Blockage in your digestive tract (pyloric or duodenal obstruction)
  • Achalasia (a rare disorder of the esophagus)
  • Enlarged prostate (prostatic hypertrophy)
  • Blockage that results in trouble urinating (obstruction of the bladder neck)
  • Myasthenia gravis (a disorder of the muscles and nerves)
  • Allergy or sensitivity to orphenadrine, aspirin, caffeine, or any other ingredient in Norgesic® Forte
    (see Full Prescribing Information for complete list)

Before taking Norgesic® Forte, tell your healthcare provider about all your medical conditions, including active viral infection (such as chicken pox, flu, or flu-like symptoms), stomach ulcer, bleeding problems, or pregnancy (or plans to become pregnant).

Talk to your healthcare provider if you are considering taking Norgesic® Forte during pregnancy. You should not take Norgesic® Forte after 29 weeks of pregnancy.

What are the possible side effects of Norgesic® Forte?

Common side effects of Norgesic® Forte include increased heart rate (tachycardia), strong or rapid heartbeat (palpitations), trouble urinating (urinary hesitancy or retention), dry mouth, blurred vision, weakness, nausea, vomiting, headache, dizziness, constipation, or drowsiness.

These are not all the possible side effects of Norgesic® Forte. Please see the Full Prescribing Information for the complete list of side effects or speak with your healthcare provider for medical advice or more information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.


Norgesic® Forte is a prescription medicine for the relief of mild to moderate pain due to acute disorders of the muscles, bones, joints, ligaments, or tendons. Norgesic® Forte tablets should be used along with rest, physical therapy, and other measures to help relieve discomfort associated with such conditions. Norgesic® Forte is not recommended in children under 12 years of age.

Please see the Full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.


Book a Telehealth Consultation Today

If you’re unable to access your own healthcare provider or don’t have one, you can schedule a telehealth consultation today from the comfort of your own home. Access a third-party healthcare professional online who can help determine if you are an appropriate candidate to receive treatment for mild to moderate acute muscle aches and pain.